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A Guide to Testosterone Therapy: From Dr. Rucker’s Reverse Med

  • Writer: Dr. Rucker
    Dr. Rucker
  • Jan 13
  • 3 min read


Testosterone therapy at Reverse Med is designed to help men regain their energy, vitality, and quality of life. With a structured protocol, bi-weekly or monthly check-ins, and required follow-up labs every six months, we ensure your treatment remains safe, effective, and tailored to your needs.


This guide outlines the injection process, the importance of ongoing health liaison check-ins, and an optional section on the use of anastrozole for managing estrogen levels.


What is Testosterone Cypionate?

Testosterone cypionate is a long-acting injectable form of testosterone prescribed for hormone replacement therapy. At Reverse Med, most patients are familiar with its benefits, which include:

  • Improved energy and stamina

  • Enhanced mood and mental clarity

  • Increased muscle mass and strength

  • Restored libido and overall vitality


Our standard protocol involves administering 1ml (200mg) of testosterone cypionate weekly via intramuscular (IM) injection.


How to Administer Your Testosterone Injection

Administering testosterone correctly ensures consistent hormone levels and minimizes the risk of side effects.


Step 1: Prepare the Syringe

  • Wash your hands thoroughly with soap and water.

  • Clean the vial’s rubber stopper with an alcohol swab.

  • Use a sterile syringe with a long enough needle for intramuscular injections (typically 1–1.5 inches).

  • Draw up 1ml (200mg) of testosterone cypionate, ensuring no air bubbles remain in the syringe.


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Step 2: Choose and Clean the Injection Site

Testosterone injections are administered intramuscularly (IM), targeting large muscle groups for optimal absorption.

  • Preferred Injection Sites:

    1. Gluteus (Buttock): The most common and recommended site due to its large muscle size.

    2. Vastus Lateralis (Thigh): A great option for patients self-administering injections.

    3. Deltoid (Upper Arm): Used less frequently but suitable for some patients.

  • Clean the injection site with an alcohol swab and let it dry completely.





Step 3: Administer the Injection

  • Insert the needle into the muscle at a 90° angle, holding it like a dart.

  • Aspirate (pull back on the plunger slightly) to ensure you haven’t hit a blood vessel. If blood appears, remove the needle, dispose of it, and start with a new syringe.

  • Slowly inject the testosterone over 5–10 seconds.

  • Remove the needle and gently press the injection site with a cotton swab or gauze.


Step 4: Dispose of the Needle

  • Discard the used syringe and needle in a sharps container.


The Importance of Bi-Weekly or Monthly Check-Ins

At Reverse Med, your health liaison plays a crucial role in your treatment. Regular check-ins ensure you stay on track and that your therapy remains effective and safe.

  1. Monitoring ProgressBi-weekly or monthly check-ins allow us to evaluate your energy levels, muscle gains, and overall well-being.

  2. Adjusting Your PlanYour health liaison will determine if adjustments are needed to your testosterone dose or if additional treatments, such as aromatase inhibitors, are required.

  3. Addressing Side EffectsAny side effects, such as water retention, mood changes, or injection site discomfort, can be discussed and addressed during these sessions.

  4. Follow-Up Labs Every 6 MonthsRoutine bloodwork every six months is required:




Optional: Taking Anastrozole Weekly

Some patients on testosterone therapy may experience elevated estrogen levels due to aromatization (the conversion of testosterone into estrogen). High estrogen can cause symptoms such as water retention, mood swings, and gynecomastia (breast tissue enlargement).

What is Anastrozole?Anastrozole is an aromatase inhibitor that helps manage estrogen levels. At Reverse Med, we may prescribe anastrozole 1x weekly for patients who need additional support in balancing their hormone levels.


How to Take Anastrozole

  • Dosage: Typically, 0.5mg to 1mg once weekly, depending on lab results and symptoms.

  • When to Take It: Anastrozole is usually taken on the same day as your testosterone injection or as advised by your health liaison.

  • Important Note: Overuse of anastrozole can lead to excessively low estrogen levels, which may cause joint pain, fatigue, and reduced libido. Always follow your prescribed dose.


Tips for Success with Testosterone Therapy

  1. Rotate Injection Sites: To prevent irritation or tissue damage, alternate injection sites weekly.

  2. Maintain Consistency: Administer your injections at the same time each week to maintain steady hormone levels.

  3. Stay Engaged: Keep up with bi-weekly or monthly check-ins and attend your 6-month lab appointments.

  4. Communicate with Your Liaison: If you experience side effects or have questions about your treatment, don’t hesitate to contact your health liaison for guidance.


Sources and References

This guide is based on established clinical practices and guidelines:

  1. Endocrine Society and American Urological Association clinical guidelines on testosterone replacement therapy.

  2. Injection safety and IM technique recommendations from the CDC.

  3. Manufacturer information for testosterone cypionate 200mg/ml.

  4. Clinical insights on the use of aromatase inhibitors like anastrozole in managing estrogen levels.


Conclusion

Testosterone therapy, when combined with regular check-ins, follow-up labs, and optional estrogen management, can help you achieve long-term success. At Reverse Med, we’re committed to providing personalized care to ensure you get the most out of your treatment.

If you have any questions about injections, side effects, or your overall progress, contact Dr. Rucker’s team at Reverse Med today. Together, we’ll keep you on track toward achieving your goals.




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