Low-Dose Naltrexone

At Reverse Med, Dr. Rucker offers Low-Dose Naltrexone (LDN) as part of our commitment to personalized and innovative healthcare solutions. LDN is a modified, lower dose of the FDA-approved medication naltrexone, traditionally used for opioid and alcohol dependence. In smaller doses, LDN has shown potential in modulating the immune system and reducing inflammation, making it a promising option for various chronic conditions.

What is Low-Dose Naltrexone?

Naltrexone is an opioid receptor antagonist that, at standard doses (50 mg or more), blocks opioid receptors to treat substance dependence. However, when administered in low doses (typically 1.5 mg to 4.5 mg), naltrexone exhibits different pharmacological properties. LDN temporarily binds to opioid receptors, leading to a rebound effect that increases the production of endorphins and enkephalins—natural peptides that modulate pain and immune function.

Potential Benefits of LDN

Dr. Rucker highlights several conditions where LDN may offer therapeutic benefits:

Autoimmune Diseases: LDN may help regulate immune responses in conditions such as multiple sclerosis, rheumatoid arthritis, and Hashimoto's thyroiditis.
Chronic Pain Syndromes: Patients with fibromyalgia and complex regional pain syndrome have reported reduced pain and improved quality of life with LDN therapy.
Inflammatory Bowel Diseases: Studies suggest that LDN can reduce inflammation and symptoms in Crohn's disease and ulcerative colitis.
Mood Disorders: By modulating neurotransmitter activity, LDN may have potential benefits in managing depression and anxiety.

Flex-Dose Tablets for Personalized Treatment

To facilitate individualized dosing, Reverse Med provides LDN in Flex-Dose Tablets. These tablets are scored to allow easy splitting into halves or quarters, enabling precise dose adjustments. This flexibility is particularly beneficial during the titration phase, ensuring that patients receive the optimal therapeutic dose with minimal side effects.

Administration and Dosage

Dr. Rucker will work closely with you to determine the appropriate starting dose and titration schedule based on your specific condition and response to therapy. LDN is typically taken orally at bedtime.

Important Considerations

Side Effects: LDN is generally well-tolerated. Some individuals may experience mild side effects such as sleep disturbances or vivid dreams during the initial stages of treatment.
Drug Interactions: Inform Dr. Rucker of all medications and supplements you are taking, as LDN may interact with certain drugs, particularly opioid-containing medications.
Contraindications: LDN is not suitable for individuals currently using opioid analgesics or those with liver failure.